Chemical constituents from the bulb of Corydalis yanhusuo W.T.Wang

Objective To isolate the chemical constituents and elucidate their structures from the bulb of Corydalis yanhusuo W.T.Wang.Methods The compounds were isolated by chromatography on silica gel,Al2O3 column and recrystallization method.NMR,TLC and ESI-MS were employed for the structure identification.Results Thirteen compounds were obtained and elucidated as:tetrahydrocorysamine(1),tetrahydrocoptisine(2),corydaline(3),tetrahydropalmatine(4),dehydrocorydali-ne(5),oxoglaucine(6),noroxyhydrastinine(7),tetrahydroberberine(8),behenic acid(9),β-sitosterol(10),daucosterol(11),vanillic acid(12),p-hydroxybenzoic acid(13),respectively.Conclusions Among these compounds,9,12,and 13 are obtained from the Corydalis genus for the first time;6,7,10 and 11 are obtained from this plant for the first time.