[A novel alkaloid from Corydalis tomentella].
Xuan-Ning Long, Feng Han, Lin Wei, Fancheng Meng, Shen-Yue Qu, Min Chen
Abstract
Xuan-Ning Long, Feng Han, Lin Wei, Fancheng Meng, Shen-Yue Qu, Min Chen
Abstract
The chemical constituents in the ethyl acetate extract of Corydalis tomentella was isolated and purified with normal and reversed phase silica gel column chromatography, Sephadex LH-20, MCI, and semi-preparative HPLC. The compound structures were identified based on spectroscopic experiments and reported papers. Finally, eighteen compounds(1-18) were obtained from C. tomentella, including 17 alkaloids and 1 terpenoid. Among them, compound 1(tomentellaine A) was a novel alkaloid. Compounds 2-5, 7-14, and 16-18 were isolated from this plant for the first time.
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The chemical constituents in the ethyl acetate extract of Corydalis tomentella was isolated and purified with normal and reversed phase silica gel column chromatography, Sephadex LH-20, MCI, and semi-preparative HPLC. The compound structures were identified based on spectroscopic experiments and reported papers. Finally, eighteen compounds(1-18) were obtained from C. tomentella, including 17 alkaloids and 1 terpenoid. Among them, compound 1(tomentellaine A) was a novel alkaloid. Compounds 2-5, 7-14, and 16-18 were isolated from this plant for the first time.
Key concepts: Corydalis, Alkaloid, Sephadex, Chromatography, Chemistry, Silica gel, Column chromatography, Tetrahydropalmatine