The features of coronary artery lesion in female patients with type 2 diabetes mellitus with coronary heart disease

Objective:To study the features and related factors of coronary artery lesion in patients with type 2 diabetes mellitus and coronary heart disease who have received coronary angiography.Method:One hundmd and sixty_four female patients were identified as coronary heart disease by coronary angiography age from 45-81(60.63±8.41)yrs.All patients were divided into diabetes mellitus group(n=41) and non_diabetes mellitus group(n=121).Compare the clinical related factors,results of coronary angiography and therapies of each group,and analyze the significance of the difference by means of Chi_squared test or T test.Result:1.The Cholesterol(TC),triglyceride(TG),low density lipoprotein (LDL) and body mass index (IBM) are all significantly higher in diabetes mellitus group than in non_diabetes mellitus group while high density lipoprotein (HDL) is higher in non_diabetes mellitus group.Incidences of hypertension,myocardial infarction,coronary heart disease are significantly higher in diabetes mellitus group than in non_diabetes mellitus group(P0.05).2.Lesions of coronary artery in each person,multi_vessel_lesions,diffuse lesions and middle_and_high_degree of lesions are all significantly higher in diabetes mellitus group than in non_diabetes mellitus group (P0.05).3.The patients in diabetes mellitus group are more likely to receive therapy of PCI and CABG.(P0.05).Conclusion:Diabetes mellitus are independent high risk factors of coronary heart disease.Severe coronary artery lesions,multi_vessel and diffuse lesions and incidence of dangerous heart occurrence such as myocardial infarction and other high risk factors increase in female patients with diabetes mellitus.