The Knoevenagel Condensation Induced by Microwave Irradiation in Ionic Liquid Solvents
Shao Guo
Abstract
Shao Guo
Abstract
The reaction rate of Knoevenagel condensation can be dramatically enhanced by microwave irradiating the reaction mixture containing an aldehyde, active methylene compound and glycine, using an ionic liquid 1 butyl 3 methylimidazonium tetrafluoroborate (BF 4) as a solvent. Eight Knoevenagel condensation products were synthesized between 5min~10min in good yields.
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The reaction rate of Knoevenagel condensation can be dramatically enhanced by microwave irradiating the reaction mixture containing an aldehyde, active methylene compound and glycine, using an ionic liquid 1 butyl 3 methylimidazonium tetrafluoroborate (BF 4) as a solvent. Eight Knoevenagel condensation products were synthesized between 5min~10min in good yields.
Key concepts: Knoevenagel condensation, Ionic liquid, Chemistry, Tetrafluoroborate, Methylene, Aldehyde, Condensation reaction, Solvent