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Application of Microwave irradiation Techniques for the Knoevenagel Condensation

Jae-Kon Kim, Pan‐Suk Kwon, TaeWoo Kwon, Sung‐Kee Chung, Jaewook Lee

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Abstract

The reaction rate of Knoevenagel condensation can be dramatically enhanced by irradiating the reaction mixture containing an aldehyde, diethyl malonate, P2O5, piperidine, and chlorobenzene with a commercial microwave oven. Six Knoevenagel condensation products were synthesized within 5–15 min in good yields.

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What this paper is about

The reaction rate of Knoevenagel condensation can be dramatically enhanced by irradiating the reaction mixture containing an aldehyde, diethyl malonate, P2O5, piperidine, and chlorobenzene with a commercial microwave oven. Six Knoevenagel condensation products were synthesized within 5–15 min in good yields.

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OpenAlex reports 24 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

The reaction rate of Knoevenagel condensation can be dramatically enhanced by irradiating the reaction mixture containing an aldehyde, diethyl malonate, P2O5, piperidine, and chlorobenzene with a commercial microwave oven. Six Knoevenagel condensation products were synthesized within 5–15 min in good yields.

Key concepts: Knoevenagel condensation, Chemistry, Diethyl malonate, Microwave irradiation, Piperidine, Aldehyde, Condensation, Microwave

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