Application of Microwave irradiation Techniques for the Knoevenagel Condensation
Jae-Kon Kim, Pan‐Suk Kwon, TaeWoo Kwon, Sung‐Kee Chung, Jaewook Lee
Abstract
Jae-Kon Kim, Pan‐Suk Kwon, TaeWoo Kwon, Sung‐Kee Chung, Jaewook Lee
Abstract
The reaction rate of Knoevenagel condensation can be dramatically enhanced by irradiating the reaction mixture containing an aldehyde, diethyl malonate, P2O5, piperidine, and chlorobenzene with a commercial microwave oven. Six Knoevenagel condensation products were synthesized within 5–15 min in good yields.
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The reaction rate of Knoevenagel condensation can be dramatically enhanced by irradiating the reaction mixture containing an aldehyde, diethyl malonate, P2O5, piperidine, and chlorobenzene with a commercial microwave oven. Six Knoevenagel condensation products were synthesized within 5–15 min in good yields.
Key concepts: Knoevenagel condensation, Chemistry, Diethyl malonate, Microwave irradiation, Piperidine, Aldehyde, Condensation, Microwave