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Quality Standard of Yiganfuzheng Capsules

Ping Wei

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Abstract

OBJECTIVE:To establish the quality standards of Yiganfuzheng capsules.METHODS:Cortex Cinnamomi, Radix Angelicae Sinensis,Radix Et Rhizoma Salviae Miltiorrhizae,Radix Et Rhizoma Ginseng in Yiganfuzheng capsules were identified by TLC and the content of 2,3,5,4'-terahydroxystilbene-2-O-β-D-Glucoside was determined by HPLC.RESULTS: Cortex Cinnamomi,Radix Angelicae Sinensis,Radix Et Rhizoma Salviae Miltiorrhizae,and Radix Et Rhizoma Ginseng could all be identified by TLC.2,3,5,4'-terahydroxystilbene-2-O-β-D-Glucoside showed good linear relationship within the range of 20.38～203.8μg·mL~(-1)(r=0.9998),and its average recovery was 103.38%,RSD=0.75%(n=6).CONCLUSION:The established standard can be used as a quality control for Yiganfuzheng capsules.

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OBJECTIVE:To establish the quality standards of Yiganfuzheng capsules.METHODS:Cortex Cinnamomi, Radix Angelicae Sinensis,Radix Et Rhizoma Salviae Miltiorrhizae,Radix Et Rhizoma Ginseng in Yiganfuzheng capsules were identified by TLC and the content of 2,3,5,4'-terahydroxystilbene-2-O-β-D-Glucoside was determined by HPLC.RESULTS: Cortex Cinnamomi,Radix Angelicae Sinensis,Radix Et Rhizoma Salviae Miltiorrhizae,and Radix Et Rhizoma Ginseng could all be identified by TLC.2,3,5,4'-terahydroxystilbene-2-O-β-D-Glucoside showed good linear relationship within the range of 20.38～203.8μg·mL~(-1)(r=0.9998),and its average recovery was 103.38%,RSD=0.75%(n=6).CONCLUSION:The established standard can be used as a quality control for Yiganfuzheng capsules.

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Available abstract

OBJECTIVE:To establish the quality standards of Yiganfuzheng capsules.METHODS:Cortex Cinnamomi, Radix Angelicae Sinensis,Radix Et Rhizoma Salviae Miltiorrhizae,Radix Et Rhizoma Ginseng in Yiganfuzheng capsules were identified by TLC and the content of 2,3,5,4'-terahydroxystilbene-2-O-β-D-Glucoside was determined by HPLC.RESULTS: Cortex Cinnamomi,Radix Angelicae Sinensis,Radix Et Rhizoma Salviae Miltiorrhizae,and Radix Et Rhizoma Ginseng could all be identified by TLC.2,3,5,4'-terahydroxystilbene-2-O-β-D-Glucoside showed good linear relationship within the range of 20.38～203.8μg·mL~(-1)(r=0.9998),and its average recovery was 103.38%,RSD=0.75%(n=6).CONCLUSION:The established standard can be used as a quality control for Yiganfuzheng capsules.

Key concepts: Radix (gastropod), Quality standard, Ginseng, Traditional medicine, Chromatography, High-performance liquid chromatography, Linear relationship, Chemistry

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