Chemical constituents in cane of Pueraria lobata
Jungui Dai
Abstract
Jungui Dai
Abstract
Objective To study the chemical constituents from the cane of Pueraria lobata.Methods The compounds were isolated by column chromatography over silica gel and purified by Sephadex LH-20 column chromatography and preparative TLC.The structures were elucidated by means of physicochemical properties and spectroscopic analyses.Results Eleven compounds were separated and identified as: dehydrovomifoliol(1),blumenol A(2),3β-hydroxy-5α,6α-epoxy-7-megastigmen-9-one(3),liquiritigenin(4),garbanzol(5),ferulaldehyde(6),2,4-dihydroxybenzaldehyde(7),4-hydroxy-2-methoxybenzaldehyde(8),(?)-tuberosin(9),coumestrol(10),and β-sitosterol(11).Conclusion Compounds 1—3 are sesquiterpenoids,which are firstly isolated from the plants of Pueraria DC.,and compounds 4—8 are obtained from the plants of Pueraria DC.for the first time.
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Objective To study the chemical constituents from the cane of Pueraria lobata.Methods The compounds were isolated by column chromatography over silica gel and purified by Sephadex LH-20 column chromatography and preparative TLC.The structures were elucidated by means of physicochemical properties and spectroscopic analyses.Results Eleven compounds were separated and identified as: dehydrovomifoliol(1),blumenol A(2),3β-hydroxy-5α,6α-epoxy-7-megastigmen-9-one(3),liquiritigenin(4),garbanzol(5),ferulaldehyde(6),2,4-dihydroxybenzaldehyde(7),4-hydroxy-2-methoxybenzaldehyde(8),(?)-tuberosin(9),coumestrol(10),and β-sitosterol(11).Conclusion Compounds 1—3 are sesquiterpenoids,which are firstly isolated from the plants of Pueraria DC.,and compounds 4—8 are obtained from the plants of Pueraria DC.for the first time.
Key concepts: Pueraria, Sephadex, Chemistry, Column chromatography, Chromatography, Lobata, Silica gel, Butenolide