2011ZhongcaoyaoRequires access

Chemical constituents in cane of Pueraria lobata

Jungui Dai

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Abstract

Objective To study the chemical constituents from the cane of Pueraria lobata.Methods The compounds were isolated by column chromatography over silica gel and purified by Sephadex LH-20 column chromatography and preparative TLC.The structures were elucidated by means of physicochemical properties and spectroscopic analyses.Results Eleven compounds were separated and identified as: dehydrovomifoliol(1),blumenol A(2),3β-hydroxy-5α,6α-epoxy-7-megastigmen-9-one(3),liquiritigenin(4),garbanzol(5),ferulaldehyde(6),2,4-dihydroxybenzaldehyde(7),4-hydroxy-2-methoxybenzaldehyde(8),(?)-tuberosin(9),coumestrol(10),and β-sitosterol(11).Conclusion Compounds 1—3 are sesquiterpenoids,which are firstly isolated from the plants of Pueraria DC.,and compounds 4—8 are obtained from the plants of Pueraria DC.for the first time.

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Objective To study the chemical constituents from the cane of Pueraria lobata.Methods The compounds were isolated by column chromatography over silica gel and purified by Sephadex LH-20 column chromatography and preparative TLC.The structures were elucidated by means of physicochemical properties and spectroscopic analyses.Results Eleven compounds were separated and identified as: dehydrovomifoliol(1),blumenol A(2),3β-hydroxy-5α,6α-epoxy-7-megastigmen-9-one(3),liquiritigenin(4),garbanzol(5),ferulaldehyde(6),2,4-dihydroxybenzaldehyde(7),4-hydroxy-2-methoxybenzaldehyde(8),(?)-tuberosin(9),coumestrol(10),and β-sitosterol(11).Conclusion Compounds 1—3 are sesquiterpenoids,which are firstly isolated from the plants of Pueraria DC.,and compounds 4—8 are obtained from the plants of Pueraria DC.for the first time.

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Available abstract

Objective To study the chemical constituents from the cane of Pueraria lobata.Methods The compounds were isolated by column chromatography over silica gel and purified by Sephadex LH-20 column chromatography and preparative TLC.The structures were elucidated by means of physicochemical properties and spectroscopic analyses.Results Eleven compounds were separated and identified as: dehydrovomifoliol(1),blumenol A(2),3β-hydroxy-5α,6α-epoxy-7-megastigmen-9-one(3),liquiritigenin(4),garbanzol(5),ferulaldehyde(6),2,4-dihydroxybenzaldehyde(7),4-hydroxy-2-methoxybenzaldehyde(8),(?)-tuberosin(9),coumestrol(10),and β-sitosterol(11).Conclusion Compounds 1—3 are sesquiterpenoids,which are firstly isolated from the plants of Pueraria DC.,and compounds 4—8 are obtained from the plants of Pueraria DC.for the first time.

Key concepts: Pueraria, Sephadex, Chemistry, Column chromatography, Chromatography, Lobata, Silica gel, Butenolide

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