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2010•Practical Preventive MedicineRequires access

Toxicological Assessment on Safety of Tea of Apoeynum venetum Leaf

Dongfang Chen

Open publisher page 1 citations

Abstract

Objective To evaluate the safety of tea of Apoeynum venetum leaf.Methods The acute toxicity,Ames test,bone marrow cell micronucleus test,mice sperm abnormality test,and 30-day feeding test were used in this study according to the procedures for toxicological assessment of food.Results The value of MTD for mice was more than 30.0 g/kg.bw,being involved in nontoxic grade.The results of Ames test,bone marrow cell micronucleus test,mice sperm abnormality test were all negative.All indexes in 30-day feeding test were not abnormal.Conclusions The tea of Apoeynum venetum leaf is safe in this study.

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What this paper is about

Objective To evaluate the safety of tea of Apoeynum venetum leaf.Methods The acute toxicity,Ames test,bone marrow cell micronucleus test,mice sperm abnormality test,and 30-day feeding test were used in this study according to the procedures for toxicological assessment of food.Results The value of MTD for mice was more than 30.0 g/kg.bw,being involved in nontoxic grade.The results of Ames test,bone marrow cell micronucleus test,mice sperm abnormality test were all negative.All indexes in 30-day feeding test were not abnormal.Conclusions The tea of Apoeynum venetum leaf is safe in this study.

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Available abstract

Objective To evaluate the safety of tea of Apoeynum venetum leaf.Methods The acute toxicity,Ames test,bone marrow cell micronucleus test,mice sperm abnormality test,and 30-day feeding test were used in this study according to the procedures for toxicological assessment of food.Results The value of MTD for mice was more than 30.0 g/kg.bw,being involved in nontoxic grade.The results of Ames test,bone marrow cell micronucleus test,mice sperm abnormality test were all negative.All indexes in 30-day feeding test were not abnormal.Conclusions The tea of Apoeynum venetum leaf is safe in this study.

Key concepts: Micronucleus test, Ames test, Sperm, Bone marrow, Abnormality, Toxicology, Medicine, Toxicity

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