Clinical analysis of in vitro fertilization and embryo transfer in infertility women with polycystic ovary syndrome

Aim:To study the effects of in vitro fertilization and embryo transfer(IVF-ET)or intracytoplasma sperm injection (ICSI) on infertility patients with polycystic ovary syndrome(PCOS) and the characteristic of PCOS in the IVF-ET course.Methods:To analyze the IVF-ET/ICSI informations of 147 patients with PCOS (157 cycles) and 865 cases (925 cycles) without PCOS (control) between Oct.2003 to Feb 2011. All patients with PCOS took oral conception(OC) or/and mateformine for 3 to 6 months before IVF-ET/ICSI.Results: In PCOS group,the number of gonadotrophin(Gn) used during the treatment was significantly less than that in the control group.In PCOS group, the number of oocyte retrieved and the cryopreserved embryos and total good embryos were all more than those in control(P0.05).One assisted reproductive technology(ART) medicine cost in PCOS group was less than that in control(t=19.653,P0.001).There were no differences in Gn using time and number of transfered embryos,pregnancy rate,multiple pregnancy rate and ovarian hyperstimulation syndrome rate between the two groups(P0.05).Conclusion: The IVF-ET outcome in patients with PCOS would be improved after taking OC to modulate the endocrine situation before IVF-ET.