Clinic Application of in Vitro Fertilization and Embryo Transfer(IVF-ET) in Infertile Patients with Polycystic Ovary Syndrome(PCOS)

【Objective】To evaluate the effect of IVF-ET or ICSI in the infertile patients with PCOS.【Methods】A retrospective analysis was performed from 31 patients with PCOS and 287 patients with tubal infertility(control group).Both groups underwent IVFET or ICSI treatment from May 2003 to May 2006 in our IVF center.The duration of stimulation,amps of Gn,the level of serum E2 on the day of HCG injection,the number of oocytes retrieved,the rates of fertilization and pregnancy,the incidence of ovarian hyperstimulation syndrome(OHSS) were compared between the two groups.【Results】The duration of stimulation,amps of Gn,.the level of serum E2 on the day of HCG injection,the number of oocytes retrieved,the fertilization rate,clinical pregnancy were not different between the two groups.But the miscarriage rate per ET was higher in PCOS group,the occurrence of OHSS was lower in PCOS group.【Conclusion】IVF-ET is an effective management for the infertile patients with PCOS after the conventional methods have failed to be conceived,but the miscarriage rate per ET is higher in PCOS patients and the occurrence of OHSS can be controlled effectively after active treatment.