Study on Dissolution Rate of Gonglaoquhuo Tablets

This paper the report that dissolution rates of Gonglaoquhuo tablest were determined to provide basis for the appraisal and control of the medicine quality. According to Chinese Pharmacopoeia(2000) dissolution method Ⅰ, the absorbance of baicalin in Gonglaoquhuo tablets was determined by using UV spectrophotometry and water as medium at 276nm. The dissolution rates of Gonglaoquhuo tablets were calculated. The parameters (T 50 、T d、m) obtained from these samples were brought for correlation analysis. The results Showcd that lhe dissolution tates of Gonglaoquhuo tablets from different batch samples were remarkably different(P0 01). determination of the dissolution rates of Gonglaoquhuo tablets should be performed for its quality control.