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2013•Journal of Chengdu Medical CollegeRequires access

Effects of Danhong Injection(DHI)on Endothelial Cells in Elderly Patients with Unstable Angina Pectoris

Lili Cai

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Abstract

Objective To investigate the effects of Danhong Injection(DHI)on endothelial cells protection in elderly patients with unstable angina pectoris,also detect the possible mechanisms.Methods 150 patients with unstable angina pectoris were randomized to trial group and control group.Besides routine therapy,DHI was applied to the patients in the trial group,Prostaglandin E1 was given intravenously to patients in the control group.Results The plasma levels of CEC,hs-CRP and Hcy in the treatment group were significantly decreased after therapy(P0.01)compared with the control group.Conclusion Danhong injection could protect the endothelial cells from injury,decrease artery inflammation and reduce the risk of artery thrombosis.

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What this paper is about

Objective To investigate the effects of Danhong Injection(DHI)on endothelial cells protection in elderly patients with unstable angina pectoris,also detect the possible mechanisms.Methods 150 patients with unstable angina pectoris were randomized to trial group and control group.Besides routine therapy,DHI was applied to the patients in the trial group,Prostaglandin E1 was given intravenously to patients in the control group.Results The plasma levels of CEC,hs-CRP and Hcy in the treatment group were significantly decreased after therapy(P0.01)compared with the control group.Conclusion Danhong injection could protect the endothelial cells from injury,decrease artery inflammation and reduce the risk of artery thrombosis.

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Available abstract

Objective To investigate the effects of Danhong Injection(DHI)on endothelial cells protection in elderly patients with unstable angina pectoris,also detect the possible mechanisms.Methods 150 patients with unstable angina pectoris were randomized to trial group and control group.Besides routine therapy,DHI was applied to the patients in the trial group,Prostaglandin E1 was given intravenously to patients in the control group.Results The plasma levels of CEC,hs-CRP and Hcy in the treatment group were significantly decreased after therapy(P0.01)compared with the control group.Conclusion Danhong injection could protect the endothelial cells from injury,decrease artery inflammation and reduce the risk of artery thrombosis.

Key concepts: Medicine, Unstable angina, Angina, Cardiology, Thrombosis, Internal medicine, Randomized controlled trial, Inflammation

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