2009•China Practical MedicineRequires access

Study about the Protective Effect of danhong injection on Vascular Endothelial Cells for the Patients of Unstable Angina Pectoris

Xu Me

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Abstract

Objective Discussion the protective effect of danhong injection on vascular endothelial cells of the patients of unstable angina pectoris.Methods 100 selected patients of unstable angina pectoris are divided into two groups,50 for test group and 50 for control group respectively.Normal therapy of angina pectoris is applied to both groups with the exception that the test group is augmented with danhong injection.Hematoid tests are given to patients for their biochemical indexes of plasma Nitric Oxide(NO)and Endothelin-1(ET-1)before and after the treatment.Results After the treatment the plasma NO index of the test group is obviously higher than that of the control group(76.58±16.12 versus 61.52±15.61).The result is significant in statistics(P0.01),while on the contrary the ET-1 is pretty lower(48.46±8.75 versus 50.83±10.31).The result is significant in statistics(P0.01),which shows the outstanding protective effect of danhong injection on vascular endothelial cells.Conclusion Danhong injection can improve patients with unstable angina pectories plasma NO levels,at the same time can reduce plasma ET-1 levels,has a good protective effect on vascular endothelial cells.

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Objective Discussion the protective effect of danhong injection on vascular endothelial cells of the patients of unstable angina pectoris.Methods 100 selected patients of unstable angina pectoris are divided into two groups,50 for test group and 50 for control group respectively.Normal therapy of angina pectoris is applied to both groups with the exception that the test group is augmented with danhong injection.Hematoid tests are given to patients for their biochemical indexes of plasma Nitric Oxide(NO)and Endothelin-1(ET-1)before and after the treatment.Results After the treatment the plasma NO index of the test group is obviously higher than that of the control group(76.58±16.12 versus 61.52±15.61).The result is significant in statistics(P0.01),while on the contrary the ET-1 is pretty lower(48.46±8.75 versus 50.83±10.31).The result is significant in statistics(P0.01),which shows the outstanding protective effect of danhong injection on vascular endothelial cells.Conclusion Danhong injection can improve patients with unstable angina pectories plasma NO levels,at the same time can reduce plasma ET-1 levels,has a good protective effect on vascular endothelial cells.

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Available abstract

Objective Discussion the protective effect of danhong injection on vascular endothelial cells of the patients of unstable angina pectoris.Methods 100 selected patients of unstable angina pectoris are divided into two groups,50 for test group and 50 for control group respectively.Normal therapy of angina pectoris is applied to both groups with the exception that the test group is augmented with danhong injection.Hematoid tests are given to patients for their biochemical indexes of plasma Nitric Oxide(NO)and Endothelin-1(ET-1)before and after the treatment.Results After the treatment the plasma NO index of the test group is obviously higher than that of the control group(76.58±16.12 versus 61.52±15.61).The result is significant in statistics(P0.01),while on the contrary the ET-1 is pretty lower(48.46±8.75 versus 50.83±10.31).The result is significant in statistics(P0.01),which shows the outstanding protective effect of danhong injection on vascular endothelial cells.Conclusion Danhong injection can improve patients with unstable angina pectories plasma NO levels,at the same time can reduce plasma ET-1 levels,has a good protective effect on vascular endothelial cells.

Key concepts: Medicine, Unstable angina, Angina, Endothelin receptor, Nitric oxide, Cardiology, Internal medicine, Endothelial dysfunction

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