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2010•Zhongguo yiyuan yongyao pingjia yu fenxiRequires access

Cefaclor versus Cefalexin in the Treatment of 120 Cases of Bacterial Respiratory Infections: A Randomized Control Trial

Jiaxin Du

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Abstract

OBJECTIVE: To evaluate the efficacy and the safety of Cefaclor sustained release tablets for bacterial respiratory infections. METHODS: 120 patients with bacterial respiratory infections were randomly assigned to receive either Cefaclor sustained release tablets ( n = 63 ) or Cefalexin extended release tablets ( n = 57 ) for 7 days. RESULTS: The effective rate and bacterial clearance rate in Cefaclor sustained release tablets treated group were 90. 4% and 88. 1% ,respectively,as compared with 75. 5% and 80. 0% ,respectively in Cefalexin extended release tablets treated group. The side effects were mild in both groups. CONCLUSION: Cefaclor sustained release tablets have remarkable efficacy for bacterial respiratory infections.

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What this paper is about

OBJECTIVE: To evaluate the efficacy and the safety of Cefaclor sustained release tablets for bacterial respiratory infections. METHODS: 120 patients with bacterial respiratory infections were randomly assigned to receive either Cefaclor sustained release tablets ( n = 63 ) or Cefalexin extended release tablets ( n = 57 ) for 7 days. RESULTS: The effective rate and bacterial clearance rate in Cefaclor sustained release tablets treated group were 90. 4% and 88. 1% ,respectively,as compared with 75. 5% and 80. 0% ,respectively in Cefalexin extended release tablets treated group. The side effects were mild in both groups. CONCLUSION: Cefaclor sustained release tablets have remarkable efficacy for bacterial respiratory infections.

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Available abstract

OBJECTIVE: To evaluate the efficacy and the safety of Cefaclor sustained release tablets for bacterial respiratory infections. METHODS: 120 patients with bacterial respiratory infections were randomly assigned to receive either Cefaclor sustained release tablets ( n = 63 ) or Cefalexin extended release tablets ( n = 57 ) for 7 days. RESULTS: The effective rate and bacterial clearance rate in Cefaclor sustained release tablets treated group were 90. 4% and 88. 1% ,respectively,as compared with 75. 5% and 80. 0% ,respectively in Cefalexin extended release tablets treated group. The side effects were mild in both groups. CONCLUSION: Cefaclor sustained release tablets have remarkable efficacy for bacterial respiratory infections.

Key concepts: Cefalexin, Cefaclor, Medicine, Respiratory system, Randomized controlled trial, Internal medicine, Cephalosporin, Antibiotics

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