Randomized double-blind labeled controlled clinical trial on compound cefaclor in treatment of acute infections of respiratory tract

[Objective] In order to evaluate the safety and efficacy of Compound Cefaclor capsules in the treatment of acute infections of respiratory tract.[Methods] A randomized double-blind labeled controlled multicenter clinical trial was conducted for the treatment of 120 patients with respiratory tract infections. In the study,60 patients were enrolled in Compound Cefaclor group while 60 patients were enrolled in Cefaclor and Bromhexine Hydrochloride group.[Results] The results showed that the cute rates were 71.67% for Compound Cefaclor group and 76.67% for Cefaclor and Bromhexine Hydrochloride group,the efficacy rates were 93.33% and 93.33%,respectively.The bacterial clearance rates were 96.15% and 97.87%,respectively.The incidence of adverse reaction was 3.33% and 1.67%,respectively.[Conclusion] Compound Cefaclor capsule and Cefaclor are both effective and convenient drugs for acute infections of respiratory tract.