Amiodarone Combined with Pravastatin in Treatment of Non-vavular Paroxysmal Atrial Fibrillation:A Clinical Study

Objective To study the effect of amiodarone combined with pravastatin for non-valvular paroxysmal atrial fibrillation.Methods Ninty-seven cases were randomly divided into treatment group (n=47) and control group(n=50).The control group was treated with amiodarone, and the treatment group with amiodarone plus pravastatin.The frequency of atrial fibrillation occurrence and the duration of atrial fibrillation,the left atrial diameter and C-reactive protein in the two groups were detected before and after treatment.Results The frequency of atrial fibrillation occurrence and the duration of atrial fibrillation after treatment were significantly decreased in the two groups (P0.05).After treatment, the left atrial diameter and C-reactive protein in the treatment group were significantly lower than those in the control group (P0.05).Conclusion Amiodarone combined with pravastatin can reduce the recurrence of paroxysmal atrial fibrillation,which is related to the anti-inflammation of pravastatin.