2013Xiandai shengwu yixue jinzhanRequires access

Function of Real-time Tissue Eastography with Qantitative Analysis for Saging Liver Fibrosis

Xiao-yu Dong

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Abstract

Objective: To evaluate the values of liver fibrosis staging of chronic hepatitis B by elastic characteristic quantities and the elasticity ratings in Real-time Tissue Elastography(RTE).Methods: The liver elasticity ratings of 140 patients with chronic hepatitis B patients were detected by RTE.The liver tissue elasticity characteristics: The average relative strain(Mean),the standard deviation of relative strain value(SD),the percentage of blue in solving area(%Area),the degrees of Blue area mixed with other colors(Comp) were determined and compared with liver biopsy pathological staging.Results: There were positive 112 cases and negative 28 cases in the liver elasticity ratings.The sensitivity and specificity of the qualitative diagnosis of liver fibrosis by RTE elasticity ratings were 96.26% and 72.73%,respectively.The correlations of Mean,SD,% Area and Comp contrast with pathological diagnosis were better than those in the conventional ultrasound(Mean: r=-0.838,P0.05;%,Area: r=0.864,P0.05).The sensitivity(RTE: 96.26% VS conventional: 64.49%)and specificity(RTE: 72.73% VS conventional: 33.33%)in the elastic ratings were much higher than those in the conventional ultrasound.Conclusion: RTE provides a new method for the evaluation of liver fibrosis,gave the liver fibrosis diagnosis means a new supplement.

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Objective: To evaluate the values of liver fibrosis staging of chronic hepatitis B by elastic characteristic quantities and the elasticity ratings in Real-time Tissue Elastography(RTE).Methods: The liver elasticity ratings of 140 patients with chronic hepatitis B patients were detected by RTE.The liver tissue elasticity characteristics: The average relative strain(Mean),the standard deviation of relative strain value(SD),the percentage of blue in solving area(%Area),the degrees of Blue area mixed with other colors(Comp) were determined and compared with liver biopsy pathological staging.Results: There were positive 112 cases and negative 28 cases in the liver elasticity ratings.The sensitivity and specificity of the qualitative diagnosis of liver fibrosis by RTE elasticity ratings were 96.26% and 72.73%,respectively.The correlations of Mean,SD,% Area and Comp contrast with pathological diagnosis were better than those in the conventional ultrasound(Mean: r=-0.838,P0.05;%,Area: r=0.864,P0.05).The sensitivity(RTE: 96.26% VS conventional: 64.49%)and specificity(RTE: 72.73% VS conventional: 33.33%)in the elastic ratings were much higher than those in the conventional ultrasound.Conclusion: RTE provides a new method for the evaluation of liver fibrosis,gave the liver fibrosis diagnosis means a new supplement.

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Available abstract

Objective: To evaluate the values of liver fibrosis staging of chronic hepatitis B by elastic characteristic quantities and the elasticity ratings in Real-time Tissue Elastography(RTE).Methods: The liver elasticity ratings of 140 patients with chronic hepatitis B patients were detected by RTE.The liver tissue elasticity characteristics: The average relative strain(Mean),the standard deviation of relative strain value(SD),the percentage of blue in solving area(%Area),the degrees of Blue area mixed with other colors(Comp) were determined and compared with liver biopsy pathological staging.Results: There were positive 112 cases and negative 28 cases in the liver elasticity ratings.The sensitivity and specificity of the qualitative diagnosis of liver fibrosis by RTE elasticity ratings were 96.26% and 72.73%,respectively.The correlations of Mean,SD,% Area and Comp contrast with pathological diagnosis were better than those in the conventional ultrasound(Mean: r=-0.838,P0.05;%,Area: r=0.864,P0.05).The sensitivity(RTE: 96.26% VS conventional: 64.49%)and specificity(RTE: 72.73% VS conventional: 33.33%)in the elastic ratings were much higher than those in the conventional ultrasound.Conclusion: RTE provides a new method for the evaluation of liver fibrosis,gave the liver fibrosis diagnosis means a new supplement.

Key concepts: Medicine, Elastography, Fibrosis, Pathological, Ultrasound, Liver fibrosis, Liver biopsy, Elasticity (physics)

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