Optimization of Extraction of Flavonoids from Chrysanthemum coronarium L.by microwave Method

[Objective]To optimize the extraction conditions of flavonoids from Chrysanthemum coronarium L.by microwave method.[Method] Single factor test was adopted to inspect the effects of ethanol concentration,solid-liquid ratio,microwave power and extraction time on the extraction rate of flavonoids from Chrysanthemum coronarium L.,and the extraction technology was optimized by orthogonal experiment.[Result]The optimum conditions for extracting flavonoids by microwave method were:60% ethanol,1∶20 solid-liquid ratio,and microwave thawing for 120 s.Under those conditions,the yield of flavonoids could reach 0.319%.[Conclusion]The microwave extraction of flavonoids from Chrysanthemum coronarium L.was simple and practical,which was time-saving,energy-conserving and high efficient.