Analysis on drug resistance of Staphylococci in hospital infection

Objective To study the pathogenicity and drug resistance status of Sphylococcus so as to offer related information to the control of hospital infection.Methods Careful identification and meticillin resistant Staphylococci(MRS) test were made to all 195 strains of staphylococci isolated from clinical specimens,and then the results and related clinical data were analyzed.Results Of all the 195 strains of staphylococci,56 strains(28.72%) were staphylococcus aureus,37(18.97%) were staphylococcus epidermidis,31(15.89%) were s.sch leiferi.Among the samples 11(19.42%) were methicillin resistant staphylococcus aureus(MRSA) and 18(12.94%) were meticillin-resistant coagulase-negative staphylococcus(MRCNS) by MRS test.The sensitive rate of coagulase-negative staphylococcus(CNS) to penicillin was very low(0.0%),the drug resistance rate of MRSA to amoxicillin and azithromycin achieved to 68.9%-85.2%,while MRCNS to cefazolin and azithromycin achieved to 57.6%-70.6%.Conclusion To understand the diversification of staphylococcus infection and variation of drug resistance promptly is necessary to get evidence for the prevention and treatment of hospital-acquired staphylococcus infection.