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2006•Journal of Medical ForumRequires access

The Relationship between the Expression of Bcl-2 and Clinical Pathology Characteristic

Nan Zhang

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Abstract

Objective To investigate the expression of Bcl-2 and the relationship between the expression and the clinical pathology characteristic in non-small cell lung cancer(NSCLC).Methods The expression of Bcl-2 was detected in 80 NSCLC samples and 40 lung benign lesion tissues as control by immunohistochemistry(S-P).Results The expression level of Bcl-2 was found to be significantly higher in NSCLC tissues than that in benign lesion tissues(P0.01);The expression level of Bcl-2 was closely related to histological classification in lung cancer patients(P(0.05)).Conclusion The increasing of Bcl-2 expression is may be related to the pathogenesis and development of lung cancer.

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What this paper is about

Objective To investigate the expression of Bcl-2 and the relationship between the expression and the clinical pathology characteristic in non-small cell lung cancer(NSCLC).Methods The expression of Bcl-2 was detected in 80 NSCLC samples and 40 lung benign lesion tissues as control by immunohistochemistry(S-P).Results The expression level of Bcl-2 was found to be significantly higher in NSCLC tissues than that in benign lesion tissues(P0.01);The expression level of Bcl-2 was closely related to histological classification in lung cancer patients(P(0.05)).Conclusion The increasing of Bcl-2 expression is may be related to the pathogenesis and development of lung cancer.

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Available abstract

Objective To investigate the expression of Bcl-2 and the relationship between the expression and the clinical pathology characteristic in non-small cell lung cancer(NSCLC).Methods The expression of Bcl-2 was detected in 80 NSCLC samples and 40 lung benign lesion tissues as control by immunohistochemistry(S-P).Results The expression level of Bcl-2 was found to be significantly higher in NSCLC tissues than that in benign lesion tissues(P0.01);The expression level of Bcl-2 was closely related to histological classification in lung cancer patients(P(0.05)).Conclusion The increasing of Bcl-2 expression is may be related to the pathogenesis and development of lung cancer.

Key concepts: Lung cancer, Immunohistochemistry, Pathology, Pathogenesis, Lesion, Lung, Medicine, Biology

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