2010China Practical MedicineRequires access

Clinical observation of different medication in the treatment of childhood asthma

Wu Fa

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Abstract

Objective To explore clinical effects of different medication in the treatment of childhood as hma. Methods Selected 98 cases of children with asthma as research objects,randomly divide these children into montelukast sodium group,budesonide group and the control group,and give them montelukast sodium 5 mg per night,aerosol budesonide 200μg/time,1 time/d,and Elgin 5 g/time,2 times/d,orally. Twelve weeks later,observed and compared the control of asthma and improvement of lung function of three groups. Results After treatment,FEV1 and PEF of Montelukast sodium group and budesonide group were significantly increased,the difference was statistically significant( P 0. 05). Compared with control group,control rate of montelukast sodium group and budesonide group was significantly higher. The difference was statistically significant ( P 0. 01). However,there was no statistically significant difference between montelukast sodium group and budes-onide group( P 0. 05). Conclusion Oral montelukast sodium and low-dose inhaled budesonide have a curative effect on controlling childhood asthma and improving lung function.

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Objective To explore clinical effects of different medication in the treatment of childhood as hma. Methods Selected 98 cases of children with asthma as research objects,randomly divide these children into montelukast sodium group,budesonide group and the control group,and give them montelukast sodium 5 mg per night,aerosol budesonide 200μg/time,1 time/d,and Elgin 5 g/time,2 times/d,orally. Twelve weeks later,observed and compared the control of asthma and improvement of lung function of three groups. Results After treatment,FEV1 and PEF of Montelukast sodium group and budesonide group were significantly increased,the difference was statistically significant( P 0. 05). Compared with control group,control rate of montelukast sodium group and budesonide group was significantly higher. The difference was statistically significant ( P 0. 01). However,there was no statistically significant difference between montelukast sodium group and budes-onide group( P 0. 05). Conclusion Oral montelukast sodium and low-dose inhaled budesonide have a curative effect on controlling childhood asthma and improving lung function.

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Available abstract

Objective To explore clinical effects of different medication in the treatment of childhood as hma. Methods Selected 98 cases of children with asthma as research objects,randomly divide these children into montelukast sodium group,budesonide group and the control group,and give them montelukast sodium 5 mg per night,aerosol budesonide 200μg/time,1 time/d,and Elgin 5 g/time,2 times/d,orally. Twelve weeks later,observed and compared the control of asthma and improvement of lung function of three groups. Results After treatment,FEV1 and PEF of Montelukast sodium group and budesonide group were significantly increased,the difference was statistically significant( P 0. 05). Compared with control group,control rate of montelukast sodium group and budesonide group was significantly higher. The difference was statistically significant ( P 0. 01). However,there was no statistically significant difference between montelukast sodium group and budes-onide group( P 0. 05). Conclusion Oral montelukast sodium and low-dose inhaled budesonide have a curative effect on controlling childhood asthma and improving lung function.

Key concepts: Budesonide, Medicine, Montelukast, Asthma, Significant difference, Lung function, Anesthesia, Clinical efficacy

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