N-terminal pro-brain natriuretic peptide and high sensitivity C-reactive protein in assessing prognosis of patients with acute myocardial infarction after primary percutaneous coronary intervention

Objective To investigate the roles of plasma N-terminal pro-brain natriuretic(NT-proBNP)and high sensitivity C-reactive protein(hs-CRP)in assessing the prognosis of patients with acute myocardial infarction(AMI)after primary percutaneous coronary intervention(PCI).Methods A total of 61 AMI patients receiving primary PCI were included in the present study.The plasma NT-proBNP and hs-CRP were measured within two weeks after primary PCI and the echocardiograms were taken at 3 days and 3 months after PCI.The vascular events were observed during hospitalization and within 3 months after PCI.Results The plasma NT-proBNP and hs-CRP levels were significantly higher in left ventricular remodeling group(left ventricular ejection fraction [ΔLVEDVI]≥20%)compared with those in left ventricular non-remodeling group(ΔLVEDVI20%,both P0.05).And NT-proBNP and hs-CRP levels were significantly higher in the group with post-PCI cardiac events compared with those in the event free group(both P0.05).Conclusion Plasma NT-proBNP and hs-CRP levels can be used to predict the prognosis of AMI patients after primary PCI.