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The Clinical Application of LEEP on Diagnosis and Treatment of Disease of Cervix

Xie Hui-jun

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Abstract

Objective To discuss the application of the loop electrosurgical excisional procedure(LEEP)in diagnosis and treatment of disease of cervix.Methods There are 262 cases who are diagnosed as moderate,severe cervical inflammation and different degree cervical intraepithelial neoplasia by the three-step screening approach.To observe the curative effect and complication,we analyzed and comparatived the pathology results between cervical conization and colposcopic multiple biopsies.Results Of the 262 case,the results of 220 case(83.97%)between cervical conization and colposcopic multiple biopsies were coincident,they are 92.3%(168/182)inflammation,100.0%(10/10)polyp,CIN Ⅰ71.1%(22/31),CIN Ⅱ12/20(60.0%)、CIN Ⅲ54.5%(6/11)and CIS 33.3%(2/6),that of other 42cases(16.03%)were discordant.2 invasive carcinoma cases were diagnosed by LEEP and radical hysterectomy was performed,8 cases were treated by panhysterectomy for CIN Ⅲ and CIS.65 cases operated with LEEP were not cytology abnormal in 24 months followed-up period.and there were 8 times pregnancy.Hemorrhage was the main postoperative complication of LEEP(5.34%).Conclusion LEEP plays a very important role in diagnosis and treatment of CIN.It can make up the defect of colposcopy.Cervical competenceervical conization of LEEP is a good way for the women with CIN and desired childbearing.

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Objective To discuss the application of the loop electrosurgical excisional procedure(LEEP)in diagnosis and treatment of disease of cervix.Methods There are 262 cases who are diagnosed as moderate,severe cervical inflammation and different degree cervical intraepithelial neoplasia by the three-step screening approach.To observe the curative effect and complication,we analyzed and comparatived the pathology results between cervical conization and colposcopic multiple biopsies.Results Of the 262 case,the results of 220 case(83.97%)between cervical conization and colposcopic multiple biopsies were coincident,they are 92.3%(168/182)inflammation,100.0%(10/10)polyp,CIN Ⅰ71.1%(22/31),CIN Ⅱ12/20(60.0%)、CIN Ⅲ54.5%(6/11)and CIS 33.3%(2/6),that of other 42cases(16.03%)were discordant.2 invasive carcinoma cases were diagnosed by LEEP and radical hysterectomy was performed,8 cases were treated by panhysterectomy for CIN Ⅲ and CIS.65 cases operated with LEEP were not cytology abnormal in 24 months followed-up period.and there were 8 times pregnancy.Hemorrhage was the main postoperative complication of LEEP(5.34%).Conclusion LEEP plays a very important role in diagnosis and treatment of CIN.It can make up the defect of colposcopy.Cervical competenceervical conization of LEEP is a good way for the women with CIN and desired childbearing.

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Available abstract

Objective To discuss the application of the loop electrosurgical excisional procedure(LEEP)in diagnosis and treatment of disease of cervix.Methods There are 262 cases who are diagnosed as moderate,severe cervical inflammation and different degree cervical intraepithelial neoplasia by the three-step screening approach.To observe the curative effect and complication,we analyzed and comparatived the pathology results between cervical conization and colposcopic multiple biopsies.Results Of the 262 case,the results of 220 case(83.97%)between cervical conization and colposcopic multiple biopsies were coincident,they are 92.3%(168/182)inflammation,100.0%(10/10)polyp,CIN Ⅰ71.1%(22/31),CIN Ⅱ12/20(60.0%)、CIN Ⅲ54.5%(6/11)and CIS 33.3%(2/6),that of other 42cases(16.03%)were discordant.2 invasive carcinoma cases were diagnosed by LEEP and radical hysterectomy was performed,8 cases were treated by panhysterectomy for CIN Ⅲ and CIS.65 cases operated with LEEP were not cytology abnormal in 24 months followed-up period.and there were 8 times pregnancy.Hemorrhage was the main postoperative complication of LEEP(5.34%).Conclusion LEEP plays a very important role in diagnosis and treatment of CIN.It can make up the defect of colposcopy.Cervical competenceervical conization of LEEP is a good way for the women with CIN and desired childbearing.

Key concepts: Medicine, Cervical intraepithelial neoplasia, Colposcopy, Loop electrosurgical excision procedure, Complication, Cervical conization, Cervix, Hysterectomy

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