Clinical Study of Therapeutic Alliance with Swibec in Treatment of Duodenal Ulcer

Objective To explore the curative effect of therapeutic alliance with omeprazole,swibec and amoxicillin for helieobaeter pylori positive duodenal ulcer.Methods 98 cases with Hp positive duodenal ulcer were randomly divided into two groups.The treatment group(n=55) was treated with omeprazole,swibec and amoxicillin,while the control group(n=43) was treated with omeprazole,metronidazole and amoxicillin.The remission rate of symptom,rate of ulcer cicatrization,eradication rate of Hp and adverse events were observed in each group.Results At the end of the treatment program,the remission rate of symptom and rate of ulcer cicatrization in treatment group was 94.55% and 89.09% respectively,and that of the control group was 81.40% and 79.07%(P0.05),while there was no significant difference in the eradication rate of Hp and the adverse effect incidence between two groups(P0.05).There was increased tendency of the eradication rate of Hp in treatment than that in control group.Conclusion Therapeutic alliance with omeprazole,swibec and amoxicillin was safe,and effective for H.Pylori positive duodenal ulcer.It was a worthy method for clinic.