2008•Zhonghua zhongyiyao xuekanRequires access

Optimization the Extraction Process of JiaoXuanLing Complex Prescription by Orthogonal Design

Liang Fang

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Abstract

Objective:To optimize the extraction process of JiaoXuanLing Complex Prescription. Methods:The optimum extraction process was investigated by the orthogonal design. The index was the yielding contents of baicalin and berberine hydrochloride in extract which were determined by HPLC. Results: The optimized extraction process was as follow,adding 10 times of 80% alcohol into meal,refluxing and extracting for 2 times,60 minutes every time. Conclution: The optimized process is simple and feasible.

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Objective:To optimize the extraction process of JiaoXuanLing Complex Prescription. Methods:The optimum extraction process was investigated by the orthogonal design. The index was the yielding contents of baicalin and berberine hydrochloride in extract which were determined by HPLC. Results: The optimized extraction process was as follow,adding 10 times of 80% alcohol into meal,refluxing and extracting for 2 times,60 minutes every time. Conclution: The optimized process is simple and feasible.

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Available abstract

Objective:To optimize the extraction process of JiaoXuanLing Complex Prescription. Methods:The optimum extraction process was investigated by the orthogonal design. The index was the yielding contents of baicalin and berberine hydrochloride in extract which were determined by HPLC. Results: The optimized extraction process was as follow,adding 10 times of 80% alcohol into meal,refluxing and extracting for 2 times,60 minutes every time. Conclution: The optimized process is simple and feasible.

Key concepts: Baicalin, Extraction (chemistry), Chromatography, Berberine hydrochloride, Process (computing), High-performance liquid chromatography, Chemistry, Mathematics

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