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Study on Extraction Process for Berberine of Kuolougenwan with Orthogonal Design

Zao Lin-lin

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Abstract

Objective:To study the optimized extraction process of berberine hydrochloride,one of the effective parts of Kuolougenwan.Method:An orthogonal experimental design L9(34) test was adopted in this study.And the content of berberine hydrochloride was determined to fit its quality standard,screening out the best method of extraction conditions.Result:The best extracting technical conditions were as follows:10 times amount of water,extraction for 2 hour and extracted 2 times.Conclusion:The optimized process is simple,fast and feasible with good stability and repeatability.

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What this paper is about

Objective:To study the optimized extraction process of berberine hydrochloride,one of the effective parts of Kuolougenwan.Method:An orthogonal experimental design L9(34) test was adopted in this study.And the content of berberine hydrochloride was determined to fit its quality standard,screening out the best method of extraction conditions.Result:The best extracting technical conditions were as follows:10 times amount of water,extraction for 2 hour and extracted 2 times.Conclusion:The optimized process is simple,fast and feasible with good stability and repeatability.

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Available abstract

Objective:To study the optimized extraction process of berberine hydrochloride,one of the effective parts of Kuolougenwan.Method:An orthogonal experimental design L9(34) test was adopted in this study.And the content of berberine hydrochloride was determined to fit its quality standard,screening out the best method of extraction conditions.Result:The best extracting technical conditions were as follows:10 times amount of water,extraction for 2 hour and extracted 2 times.Conclusion:The optimized process is simple,fast and feasible with good stability and repeatability.

Key concepts: Berberine hydrochloride, Repeatability, Extraction (chemistry), Berberine, Chromatography, Process (computing), Quality standard, Mathematics

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