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Progress in RNAi and its application

Hongsheng Li

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Abstract

RNA interference(RNAi)is a post-transcriptional gene silencing induced by introduction of double-stranded RNA(dsRNA).It's a process of sequence-specific gene silence,which can specifically and effectively suppress the activity of corresponding mRNAs induced by double-stranded dsRNA.This is a highly specifically mechanism that involved in kinds of proteins.It's not only be a powerful tool in gene functional research,but also provides a new technique for gene therapy.RNAi not only is a powerful method for studying genes,but also offers new techniques for the therapy of specific gene.This paper introduces the research progress in the mechanisms and application of RNAi.

About this research paper

What this paper is about

RNA interference(RNAi)is a post-transcriptional gene silencing induced by introduction of double-stranded RNA(dsRNA).It's a process of sequence-specific gene silence,which can specifically and effectively suppress the activity of corresponding mRNAs induced by double-stranded dsRNA.This is a highly specifically mechanism that involved in kinds of proteins.It's not only be a powerful tool in gene functional research,but also provides a new technique for gene therapy.RNAi not only is a powerful method for studying genes,but also offers new techniques for the therapy of specific gene.This paper introduces the research progress in the mechanisms and application of RNAi.

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Available abstract

RNA interference(RNAi)is a post-transcriptional gene silencing induced by introduction of double-stranded RNA(dsRNA).It's a process of sequence-specific gene silence,which can specifically and effectively suppress the activity of corresponding mRNAs induced by double-stranded dsRNA.This is a highly specifically mechanism that involved in kinds of proteins.It's not only be a powerful tool in gene functional research,but also provides a new technique for gene therapy.RNAi not only is a powerful method for studying genes,but also offers new techniques for the therapy of specific gene.This paper introduces the research progress in the mechanisms and application of RNAi.

Key concepts: RNA interference, RNA silencing, Gene silencing, Gene, Biology, Computational biology, RNA, DNA-directed RNA interference

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