2000Journal of Qufu Normal UniversityRequires access

EFFECT OF β-AMYLOID PROTEIN ON LEARNING AND MEMORY IN RATS

Ya Li

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Abstract

This paper is intended to study the effect of β _amyloid protein on learning and memory in rats. The behaviors of rats were measured by using open field and Y_maze, the contens of SOD and MDA were also measured. The spontaneous activity and response of the β _AP group rats to novel environment in the open field were significantly decreased, and the ability of Y_maze discrimination learning_memory were attenuated. The content of SOD decreased and MDA increased, P 0.05 compared with control group. β _amyloid protein induces the significant reduction of learning_memory ability in rats.

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What this paper is about

This paper is intended to study the effect of β _amyloid protein on learning and memory in rats. The behaviors of rats were measured by using open field and Y_maze, the contens of SOD and MDA were also measured. The spontaneous activity and response of the β _AP group rats to novel environment in the open field were significantly decreased, and the ability of Y_maze discrimination learning_memory were attenuated. The content of SOD decreased and MDA increased, P 0.05 compared with control group. β _amyloid protein induces the significant reduction of learning_memory ability in rats.

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Available abstract

This paper is intended to study the effect of β _amyloid protein on learning and memory in rats. The behaviors of rats were measured by using open field and Y_maze, the contens of SOD and MDA were also measured. The spontaneous activity and response of the β _AP group rats to novel environment in the open field were significantly decreased, and the ability of Y_maze discrimination learning_memory were attenuated. The content of SOD decreased and MDA increased, P 0.05 compared with control group. β _amyloid protein induces the significant reduction of learning_memory ability in rats.

Key concepts: Open field, Amyloid (mycology), Endocrinology, Internal medicine, Psychology, Chemistry, Medicine, Inorganic chemistry

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