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Study on Quality Standard of Chuandanling Capsules

Shudong Wang

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Abstract

OBJECTIVE:To establish the quality standard of Chuandanling capsules.METHODS:Qualitative identification of Salvia miltiorrhiza was conducted by TLC.The content of adenosine was determined by HPLC.RESULTS:The developed TLC spots were clear,well-separated and free from interference of negative sample.The linear range of adenosine was 20.42～102.10 μg · mL-1(r=0.999 9)with an average recovery of 101.8%(RSD=2.05%,n=9).CONCLUSION:The established standard can be used for quality control of Chuandanling capsules.

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OBJECTIVE:To establish the quality standard of Chuandanling capsules.METHODS:Qualitative identification of Salvia miltiorrhiza was conducted by TLC.The content of adenosine was determined by HPLC.RESULTS:The developed TLC spots were clear,well-separated and free from interference of negative sample.The linear range of adenosine was 20.42～102.10 μg · mL-1(r=0.999 9)with an average recovery of 101.8%(RSD=2.05%,n=9).CONCLUSION:The established standard can be used for quality control of Chuandanling capsules.

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Available abstract

OBJECTIVE:To establish the quality standard of Chuandanling capsules.METHODS:Qualitative identification of Salvia miltiorrhiza was conducted by TLC.The content of adenosine was determined by HPLC.RESULTS:The developed TLC spots were clear,well-separated and free from interference of negative sample.The linear range of adenosine was 20.42～102.10 μg · mL-1(r=0.999 9)with an average recovery of 101.8%(RSD=2.05%,n=9).CONCLUSION:The established standard can be used for quality control of Chuandanling capsules.

Key concepts: Quality standard, Salvia miltiorrhiza, Chromatography, Linear range, Linear relationship, Chemistry, High-performance liquid chromatography, Mathematics

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