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2004•Journal of Qilu OncologyRequires access

Progress in the study of vascular endothelial growth factor-C and its correlation with lymphangiogenesis and lymph node metastasis of malignany tumor

Liang Zhi-qing

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Abstract

Vascular endothelial growth factor- C(VEGF-C) is differential regulative factor of blood and lymphatic vessels,its structure having homology with VEGF.VEGF-C play roles via binding VEGR-2 and VEGFR-3.In the recent years,studys indicate that VEGF-C mediates tumour′s lymphangiogenesis via binding VEGFR-3,and in relation to lymphatic vessel involvement and lymph node metastasis.

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What this paper is about

Vascular endothelial growth factor- C(VEGF-C) is differential regulative factor of blood and lymphatic vessels,its structure having homology with VEGF.VEGF-C play roles via binding VEGR-2 and VEGFR-3.In the recent years,studys indicate that VEGF-C mediates tumour′s lymphangiogenesis via binding VEGFR-3,and in relation to lymphatic vessel involvement and lymph node metastasis.

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Available abstract

Vascular endothelial growth factor- C(VEGF-C) is differential regulative factor of blood and lymphatic vessels,its structure having homology with VEGF.VEGF-C play roles via binding VEGR-2 and VEGFR-3.In the recent years,studys indicate that VEGF-C mediates tumour′s lymphangiogenesis via binding VEGFR-3,and in relation to lymphatic vessel involvement and lymph node metastasis.

Key concepts: Lymphangiogenesis, Vascular endothelial growth factor C, Lymphatic system, Lymphatic vessel, Lymphatic Endothelium, Lymph node metastasis, Lymph node, VEGF receptors

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Progress in the study of vascular endothelial growth factor-C and its correlation with lymphangiogenesis and lymph node metastasis of malignany tumor — Research Paper | ScholarLens