Studies on the Origin-boiling with Vinegar Technology of Rhizoma Coridalis

Objective To optimize the origin-boiling with vinegar technology.Methods Single-factor experiment was carried out with temperature,vinegar volume and mixing time at first,orthogonal experiment was carried out with vinegar volume,mixing time and particle size as factors of the orthogonal experiment design.HPLC was used to determine the contents of tetrahydropalmatine,protopine and dehydrocorydaline which were the three main active ingredients in Rhizoma Corydalis.At last,the optimum origin-boiling with vinegar technology of Rhizoma Coridalis was obtained.Results The optimum origin-boiling with vinegar technology of Rhizoma Coridalis was that the small Corydalis was added 40% vinegar and infiltrated 4h and boiled,the big ones was processed after breaking.Conclusion The optimum origin-boiling with vinegar technology of Rhizoma Coridalis is simple,easy and stably.