Sichuan Provincial of antimicrobial Resistant Investigation Net 2011 annual report:Bacterial drug resistance surveillance in West Sichuan

To summarize the drug resistance of clinical isolates in western sichuan of china with 17 hospitals in 2011. Isolates were cultured by routine methods and identified by the semi-automatic or automatic bacteria analysis system.Drug susceptibility test was according to CLSI standards.Data statistic and analysis used WHONET5.4 software. 20079 strains were isolated,which included 14454(71.99%) Gram-negative strains,and 5625(28.01%) Gram-positive strains.The top ten pathogens were E.coli,K.pneumonia,P.aeruginosa,S.aureus,A.baumannii,S.epidermidis,E.faecalis,S.pne,E.faecium and H.influ.No linezolid-resistant Staphylococcus strains was found.The drug resistant rates of Enterococcus faecalis to teicoplanin and vancomycin were 1.30% and 0.70%,Enterococcus faecium were 5.40% and 4.00% respectively. ESBLs-producing Enterobacteriaceae and the multiple drug-resistant bacteria fermentation of pseudomonas aeruginosa and acinetobacter baumannii were increasing year by year.MRS and glycopeptides resistant Enterococcus were the difficult points of Antibacterial drug therapy.Therefore,reasonable choice of antimicrobial agents should be based on the bacterial resistant drug phenotype detection and drug susceptibility test results against bacteria infection.