Association between serum uric acid and coronary heart disease

AIM To analyze the association of serum uric acid with coronary heart disease(CAD).METHODS One hundred and forty-two patients with CHD confirmed by angiography and 92 control subjects without CHD were included in this study and serum uric acid and blood lipid were determined.The risk factors of coronary heart disease: gender,age,smoking,hypertension and diabetes mellitus were registered.RESULTS The serum uric acid level in CHD patients was markedly higher than that in control subjects(P0.01). The correlation analysis results showed that the serum uric acid level was positively and significantly related to the coronary stenosis index,age,hypertension,diabetes mellitus,TC and HDL-c(P0.05 or P0.01,respectivetly).Multivariate Logistic and stepwise regression analysis showed that the serum uric acid was not markedly related with the occurrence of CHD and the coronary stenosis index.CONCLUSION Elevated serum uric acid is not an independent risk factor for CHD.