Isolation and identification of chemical constituents of Polygonum perfoliatum L.
Ronglin Zhang, Sun Xiaocui, LI Wen-xin, WU Li-jun, Jian Huang, Sun Bohang
Abstract
Ronglin Zhang, Sun Xiaocui, LI Wen-xin, WU Li-jun, Jian Huang, Sun Bohang
Abstract
Objective To study the chemical constituents of Polygonum perfoliatum L.Methods The constituents of the ethyl acetate-soluble and n-BuOH-soluble portions of the 70% ethanol extract of Polygonum perfoliatum L.were isolated and purified by various chromatographic methods.The structures were confirmed on the basis of physico-chemical properrties and spectroscopic data.Results Seven compounds were isolated and identified as kaempferol(1),quercetin(2),avicularin(3),quercetin-3-O-β-D-glucuronide 6″-methyl ester(4),quercetin-3-O-β-D-glucuronide 6″-butyl ester(5),kaempferol-3-O-rutinoside(6) and rutin(7).Conclusions Compound 5 is obtained from this genus for the first time;Compounds 3,6 and 7 are isolated from this plant for the first time.
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Objective To study the chemical constituents of Polygonum perfoliatum L.Methods The constituents of the ethyl acetate-soluble and n-BuOH-soluble portions of the 70% ethanol extract of Polygonum perfoliatum L.were isolated and purified by various chromatographic methods.The structures were confirmed on the basis of physico-chemical properrties and spectroscopic data.Results Seven compounds were isolated and identified as kaempferol(1),quercetin(2),avicularin(3),quercetin-3-O-β-D-glucuronide 6″-methyl ester(4),quercetin-3-O-β-D-glucuronide 6″-butyl ester(5),kaempferol-3-O-rutinoside(6) and rutin(7).Conclusions Compound 5 is obtained from this genus for the first time;Compounds 3,6 and 7 are isolated from this plant for the first time.
Key concepts: Rutin, Quercetin, Kaempferol, Chemistry, Ethyl acetate, Polygonaceae, Polygonum, Chromatography