2005•Heilongjiang yiyao kexueRequires access

Measurement of serum TNFα,IL-6 and IL-8 levels and its significance in patients with chronic hepatitis B

Zian Yang

Abstract

Objective:To study the relationship between serum TNFα,IL-6 and IL-8 levels in patients with chronic hepatitis B(CHB). Methods:The serum TNFα,IL-6 and IL-8 levels in 65 patients with CHB and 30 normal controls were measured by radioimmunoassay.Results:The TNFα,IL-6 and IL-8 levels were significantly higher than those of normal controls(P0.01).A positive relation was found between serum TNFα,IL-6 and IL-8 levels.Conclusion: TNFα,IL-6 and IL-8 participate in the injury course of CHB immune,and the measurement of serum TNFα,IL-6 and IL-8 levels has clinical value for the judgement of CHB patient's condition and their prognosis.

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Key concepts: Medicine, Radioimmunoassay, Interleukin 10, Clinical significance, Tumor necrosis factor alpha, Chronic hepatitis, Immune system, Internal medicine