Evaluation of Clinical Efficacy on Erythrotelangiectatic Rosacea with ELOS Combined with Tacrolimus

Objective: To investigate the efficacy of ELOS combined with Tacrol-imus in treatment of Erythrotelangiectatic rosacea. Methods the treatment group wer-e treated with ELOS for 5 times and 0.03% Tacrolimus ointment for 6 weeks. the con-trol group were treated wit 0.03% Tacrolimus ointment for 6 weeks. After continues treatment for 2、4、6、12 weeks, we analyzed and compared the treatment effects of the two groups. Results The effective rate of the treatment group was 33.33%,6.67%、90.00%、93.33%,respectively in 2, 4, 6,12 weeks after treatment. The effective rate in control group was significantly different than that in treatment group( P 0.05).The score of erythema in group sign-ifcantly decreased in 2 weeks after treatment( P 0.05).19 cases(35.18%) had burning and itching after using Tacrolimus in the first weeks treatment.13 cases(43.33%) were found the erythema expanded after the treat-ment of ELOS,but eased up quickly after continuous treatment of cold. Conclusion ELOS combined with Tacrolimus can make a significant improvements in treatment of Erythrotelangiectatic rosacea: work fast, make a high cure rate and have a stable effects.