Expression and significance of squamous cell carcinoma antigen in non-malignant gynecological diseases

Objective To investigate the expression and clinical significance of peripheral blood squamous cell carcinoma antigen(SCCAg) in non-malignant gynecological diseases. Methods According to the inclusion and exclusion criteria, 775 patients were recruited in our study. The concentrations of serum SCCAg of the patients were detected by chemiluminescent immunoassay method. Results There were totally 155 subjects whose SCCAg concentrations were higher than the normal reference value 2.00 ng/ml. The benign lesions involved in cervix, fallopian tubes, pelvic, uterus, ovaries、vagina and other parts. Conclusion Elevated SCCAg concentration and the increased range can not be used as the basis for the diagnosis of cervical cancer, and need to be combined with other examination.