Expermental Research of Yinchen Elixation' s Protective Effect on Liver Injury

Objective To research the protective effect and mechanism of yinchen elixation on liver injury. Methods The rats model was established by intraabdominal injection of perchlormethane and treated with Yinchen elixation in different dosage. The SDH and SOD activities and MDA level in serum were measured. Results In treated groups the MDA level and SDH activity were obviously decreased but the SOD activity was increased , and the relieve degree of liver injury showed a remarkable dose-relationship. Conclusion Yinchen elixation has good protective effect on rat with acute liver injury by perchlormethane, the effect is associated with the dosage. The mechanism is probably relating to its inhibiting the lipid peroxidation.