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2004•Journal of Zhenjiang Medical CollegeRequires access

The Detection of Serum MMP-3 in Cerebral Infarction

Xiaohua Xiao

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Abstract

Objective: To investigate the role and clinical significance of serum MMP-3 in cerebral infarction. Methods: Serum MMP-3 levels were measured in 59 cerebral infarction patients (during 24 h～15 days of the onset) and 32 healthy people by ELISA. Results: The level of MMP-3 during 24 h～5 days of the cerebral infarction is higher than those of control ( P 0 05). No obvious relationship were observed between the levels of MMP-3 and the fast blood sugar (FBS),total serum cholesterol,and serum glycerol. Conclusion : MMP-3 may contribute the pathologic course in the early stage of cerebral infarction,and the level of MM P-3 is correlated with the clinical course of the disease.

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What this paper is about

Objective: To investigate the role and clinical significance of serum MMP-3 in cerebral infarction. Methods: Serum MMP-3 levels were measured in 59 cerebral infarction patients (during 24 h～15 days of the onset) and 32 healthy people by ELISA. Results: The level of MMP-3 during 24 h～5 days of the cerebral infarction is higher than those of control ( P 0 05). No obvious relationship were observed between the levels of MMP-3 and the fast blood sugar (FBS),total serum cholesterol,and serum glycerol. Conclusion : MMP-3 may contribute the pathologic course in the early stage of cerebral infarction,and the level of MM P-3 is correlated with the clinical course of the disease.

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Available abstract

Objective: To investigate the role and clinical significance of serum MMP-3 in cerebral infarction. Methods: Serum MMP-3 levels were measured in 59 cerebral infarction patients (during 24 h～15 days of the onset) and 32 healthy people by ELISA. Results: The level of MMP-3 during 24 h～5 days of the cerebral infarction is higher than those of control ( P 0 05). No obvious relationship were observed between the levels of MMP-3 and the fast blood sugar (FBS),total serum cholesterol,and serum glycerol. Conclusion : MMP-3 may contribute the pathologic course in the early stage of cerebral infarction,and the level of MM P-3 is correlated with the clinical course of the disease.

Key concepts: Cerebral infarction, Medicine, Internal medicine, Matrix metalloproteinase, Blood sugar, Clinical significance, Fasting blood sugar, Infarction

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