Mycoplasmacausing urogenital tract infections in Shaoxing and analysis of drug resistance

OBJECTIVE To analyze the infection status and drug resistance of Ureaplasma urealyticum(Uu) and Mycoplasma hominis(Mh) in urogenital tract so as to provide experimental evidence for the clinical treatment.METHODS The secretion specimen was identified and their antibiotic susceptibility was detected by using Mycoplasma identification and drug susceptibility kit 1ST2.RESULTS A total of 683 cases were involved in the study,the positive rate of Mycoplasma was 54.76%(374 cases).The positive detection rates of Uu,Mh,and Uu+Mh were 72.19%,14.97%,and 12.04%.The positive rates of the male and female were 28.57% and 70.75%,respectively,the difference was statistically significant(P0.01);the patients were mainly aged between 20 and 40 years.Mycoplasma varied in the drug sensitivity,the susceptibility rate of Uu to pristinamycin was the highest(99.26%),the drug susceptibility rates to tetracyclines,and josamycin were 97.04%,91.85%,85.93%,and 69.26%,respectively.The drug resistance rate of Mh or Uu+Mh was higher than that of Uu.CONCLUSION The urogenital tract infections are mainly caused by Uu.The infection rate of the female is significantly higher than that of the male.Mycoplasma have produced drug resistance in a certain degree.It is necessary to carry out the culture and the drug susceptibility testing for Mycoplasma and guide the reasonable clinical medication so as to effectively improve the cure rate and control the emergence of drug resistant strains.