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2013•Chinese Journal of Clinical Rational Drug UseRequires access

Analysis of 570 cases of adverse drug reaction in our hospital in 2011

Yu Wang

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Abstract

Objective To investigate the characteristics and regularity of adverse drug reaction (ADR) in our hospital to promote a rational clinical drug use.Methods By retrospective study method,570 ADR cases from our hospital in 2011 were analyzed statistically.Results ADR mostly occurred in patients aged above 60 years old (191 cases,33.51%).ADR cases were mostly caused by intravenous administration (527 cases,92.46%).Antimicrobial drugs took up the first place among ADR-inducing drugs (298 cases,52.28%).Lesion of skin and appendants were the most common clinical manifestations(322 cases,56.49%).Conclusion Great importance should be attached to ADR monitoring and rational drug use to reduce or avoid the occurrences of ADR.

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What this paper is about

Objective To investigate the characteristics and regularity of adverse drug reaction (ADR) in our hospital to promote a rational clinical drug use.Methods By retrospective study method,570 ADR cases from our hospital in 2011 were analyzed statistically.Results ADR mostly occurred in patients aged above 60 years old (191 cases,33.51%).ADR cases were mostly caused by intravenous administration (527 cases,92.46%).Antimicrobial drugs took up the first place among ADR-inducing drugs (298 cases,52.28%).Lesion of skin and appendants were the most common clinical manifestations(322 cases,56.49%).Conclusion Great importance should be attached to ADR monitoring and rational drug use to reduce or avoid the occurrences of ADR.

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Available abstract

Objective To investigate the characteristics and regularity of adverse drug reaction (ADR) in our hospital to promote a rational clinical drug use.Methods By retrospective study method,570 ADR cases from our hospital in 2011 were analyzed statistically.Results ADR mostly occurred in patients aged above 60 years old (191 cases,33.51%).ADR cases were mostly caused by intravenous administration (527 cases,92.46%).Antimicrobial drugs took up the first place among ADR-inducing drugs (298 cases,52.28%).Lesion of skin and appendants were the most common clinical manifestations(322 cases,56.49%).Conclusion Great importance should be attached to ADR monitoring and rational drug use to reduce or avoid the occurrences of ADR.

Key concepts: Medicine, Drug, Adverse drug reaction, Drug reaction, Adverse effect, Intravenous route, Internal medicine, Pharmacology

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