Clinical observation of sufentanil as supptement to anaesthesia in painless abortion

Objective:To evaluate efficacy and safety of sufentanil as supplement to propofol anaesthesia in painless abortion.Methods:60 ASA Ⅰ-Ⅱ pregnant women undergoing painless abortion were and randomly divided into treatment group(n=30) and control group(n=30).Pregnant stage was in the first or second months.In the control group,patients were administrated intravenously propofol and fentanyl.In the treatment group,sufentanil was used in combination with propofol.Both groups were infused intravenously by two phases,in first phases drug was used until patients were deeply sedated,in second phase(when uterocervical dilation)50% initial dose was boosted.Blood pressure,heart rate,SpO_2,Breath frequency,revival time,propofol dosage,post-operative nausea and vomiting,vertigo and postoperative uterotonic pain(adopt VAS grade)in two groups were compared in inducing and maintaining phases.Results:Propofol dosage,postoperative uterotonic pain and rate of breath inhibition in treated group were less than those in control group(P0.05).However,it was of no statistical significances in two groups for data of blood pressure,heart rate and SpO_2.Conclusions:Sufentanil can reduce propofol dosage and respiratory inhibition rate,strengthen analgesia effect of propofol without more side effects when used as supplement to propofol anesthesia in painless induced abortion.