Effect of propofol combined with sufentanil,remifentanil and fentanyl on painless abortion

Objective To observe the effect of propofol combined with sufentanil,remifentanil,fentanyl intravenous anesthesia on painless abortion.Methods 92 abortion patients were randomly divided into 3 groups.Group S( n =31) received propofol combined with sufentanil anesthesia; group R( n = 31) received propofol combined with remifentanil; group F( n = 30) received propofol combined fentanyl.The MAP,HR,SpO2,dose of propofol,awake time,and the visual analog scale( VAS) score were recorded at different time points.The adverse reactions were observed closely.Results After anesthesia,The MAP,HR,SpO2 of the three groups decreased significantly,and SpO2in group R was significantly lower than the other two groups.The dose of propofol in group R was less than the other two groups; VAS score in group S was the lowest.There was no significant difference in awake time and VAS scores at the time of awake among the three groups.No significant difference was found in body movement,severe body movement,hypotension,bradycardia among the three groups.The occurrence rate of hypoxemia in group R was the highest( 25.81%).Conclusion Sufentanil,remifentanil,fentanyl combined propofol for painless abortion has good narcotic and analgesic effect with high security,but sufentanil combined propofol can provide more stable vital signs with rapid postoperative recovery,it can be regarded as the best compatibility.