ScholarLens Back to search
2011•Journal of Chinese OncologyRequires access

Expression of S100A4 Protein in Colon Adenoma and Colon Carcinoma

Jianhao Hu

Open publisher page 0 citations

Abstract

[Purpose] To investigate the expression of S100A4 protein in colon adenoma and colon carcinoma and their clinical significance.[Methods] The expression of S100A4 protein was detected by immunohistochemistry in 15 cases with normal intestinal mucosa,80 case with colon adenoma and 60 cases with colon carcinoma.[Results] There was negative S100A4 expression in normal intestinal mucosa.The positive expression rate of S100A4 was 16.25% in colon adenoma and 56.67% in colon carcinoma.[Conclusion] The expression of S100A4 protein is closely related to carcinogenesis and progress in colon adenoma and colon carcinoma.S100A4 protein is an useful marker to forecast the progress of colon tumor.

About this research paper

What this paper is about

[Purpose] To investigate the expression of S100A4 protein in colon adenoma and colon carcinoma and their clinical significance.[Methods] The expression of S100A4 protein was detected by immunohistochemistry in 15 cases with normal intestinal mucosa,80 case with colon adenoma and 60 cases with colon carcinoma.[Results] There was negative S100A4 expression in normal intestinal mucosa.The positive expression rate of S100A4 was 16.25% in colon adenoma and 56.67% in colon carcinoma.[Conclusion] The expression of S100A4 protein is closely related to carcinogenesis and progress in colon adenoma and colon carcinoma.S100A4 protein is an useful marker to forecast the progress of colon tumor.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

[Purpose] To investigate the expression of S100A4 protein in colon adenoma and colon carcinoma and their clinical significance.[Methods] The expression of S100A4 protein was detected by immunohistochemistry in 15 cases with normal intestinal mucosa,80 case with colon adenoma and 60 cases with colon carcinoma.[Results] There was negative S100A4 expression in normal intestinal mucosa.The positive expression rate of S100A4 was 16.25% in colon adenoma and 56.67% in colon carcinoma.[Conclusion] The expression of S100A4 protein is closely related to carcinogenesis and progress in colon adenoma and colon carcinoma.S100A4 protein is an useful marker to forecast the progress of colon tumor.

Key concepts: Medicine, Immunohistochemistry, Adenoma, Colorectal adenoma, Carcinoma, Colorectal cancer, Pathology, Carcinogenesis

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Expression of S100A4 Protein in Colon Adenoma and Colon Carcinoma — Research Paper | ScholarLens