Efficacy of nifedipine sustained release tablets treating hypertension and fiabetes mellitus

Objective To observe the clinical efficacy of nifedipine sustained release tablets treating hypertension and diabetes mellitus. Methods Fifty patients with hypertension and diabetes mellitus treated in our hospital from January 2011 to July 2012 were selected as the research objects and were randomly divided into research group and the control group, each group of 25 cases. Two groups of patients were treated with other medicines on the basis of convential treatment of controlling blood sugar, in which the research group were treated with nifedipine sustained release tablets, and the control group were treated with losartan. 8 weeks for the treatment on patients in two groups was one course of treatment. Blood pressure, heart rate, Scr and BUN before and after treatment for two groups of patietns were detected, and the clinical effect was observed and compared. Results The hear rate, Scr and BUN before and after treatment between the two groups, there was no statistically significant difference (P 0.05). For systolic pressure and diastolic pressure, there was no evident difference between two groups, which had statistical significance (P 0.05). In addition, there was evidient difference betwee two groups for the total effective rate, and the research group was better than the control group, which had statistical significance (P 0.05). Conclusion Nifedipine sustained release tablets treating hypertension and diabetes mellitus not only has better antihypertensive effect, but also has no evident adverse reactions, which is worthy of promotion and application.