Cost-minimization analysis of sequential therapy of urinary system infection with levofloxacin

Objective:To evaluate cost-effectiveness of two therapeutic schemes of levofloxacin in the treatment of urinary system infection.Methods: Seventy seven patients with urinary system infection were randomly divided into 2 groups.One group(treatment group) took the sequential therapy with levofloxacin and the other(control group) took pure injection of levofloxacin.Therapeutic effectiveness and adverse drug reaction(ADR) were observed and a cost-minimization analysis was performed for the 2 groups.Results: There were no significant differences between 2 groups in therapeutic effectiveness,bacterial clearance and incidence of ADR(P0.05).The cost of treatment group and control group were 172.14 yuan and 353.50 yuan,respectively.The cost-effectiveness ratios of 2 groups were 187.31 and 372.11,respectively.Conclusion: Sequential therapy with levofloxacin was better than pure injection in the treatment of urinary system infection.