2014•Unpublished venueRequires access
INFLUENCE OF RHUBARB WATER EXTRACT IN DIFFERENT DECOCTING TIME ON UTERUS INDEX,OVARY INDEX AND BODY MASS INDEX
Liu Meng-ji
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Abstract
Objective:To observe the inf luence of Rhubarb water extract in different decocting time on uterus index,ovary index and body mass index.Methods:70 4-week old female SD rats were randomly divided into normal control group,Rhubarb 0.5g/kg,1.0 g/kg and 2.0 g/kg group respectively decocting 10 min and 30 min.All the rats were lavaged with corresponding drugs for 30 days and then detected the uterus index,ovary index and body mass index of rats in each group.Results:The uterus index,ovary index andbody mass index of rats in each dose group of Rhubarb decoction 10 min,2.0g/kg group of Rhubarb decoction 30 min were obviously lower than that of rats in normal control group(P0.05).Different dose Rhubarb of same decocting time:decoction 30 min,the uterus index,ovary index and body mass index of rats in 2.0g/kg group were obviously lower than that of rats in 0.5g/kg group(P 0.05);decoction 10 min,the uterus index,ovary index and body mass index of rats in 2.0g/kg and 1.0g/kg group were obviously lower than that of rats in 0.5g/kg group(P0.05).Different decocting time of same dose Rhubarb:The uterus index,ovary index and body mass index of rats in each dose group of decoction 10 min were obviously lower than that of rats in each dose group of decoction 30min(P 0.05).Conclusions:Rhubarb water extract in different decocting time can cause certain inf luences on uterus index,ovary index and weight gain,and the impacts are related to decocting time and dose.