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2014•Strait Pharmaceutical JournalRequires access

Studies on preparation technology of Fructus Forsythiae and Flos Fonicerae extrat

Wang Wenmin

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Abstract

OBJECTIVE To optimize the process of Flos Lonicerae,Lructus Forsythiae extract for formulation. METHODS The orthogonal experimental method was applied for optimizing process of water-extract-purification,and the content of chlorphenamine maleate and forsythin were tested by HPLC as infactors. RESULTS The optimized process was: add water for 10 times、8 times of the quantity of medicinal materials and mariate time was 2h、 1. 5h respectively; relative density of proportion of water extraction cream enrichment was 1. 25. CONCLUSION The extraction rate of active material using optimized process is higher and suit for manufacturing.

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What this paper is about

OBJECTIVE To optimize the process of Flos Lonicerae,Lructus Forsythiae extract for formulation. METHODS The orthogonal experimental method was applied for optimizing process of water-extract-purification,and the content of chlorphenamine maleate and forsythin were tested by HPLC as infactors. RESULTS The optimized process was: add water for 10 times、8 times of the quantity of medicinal materials and mariate time was 2h、 1. 5h respectively; relative density of proportion of water extraction cream enrichment was 1. 25. CONCLUSION The extraction rate of active material using optimized process is higher and suit for manufacturing.

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Available abstract

OBJECTIVE To optimize the process of Flos Lonicerae,Lructus Forsythiae extract for formulation. METHODS The orthogonal experimental method was applied for optimizing process of water-extract-purification,and the content of chlorphenamine maleate and forsythin were tested by HPLC as infactors. RESULTS The optimized process was: add water for 10 times、8 times of the quantity of medicinal materials and mariate time was 2h、 1. 5h respectively; relative density of proportion of water extraction cream enrichment was 1. 25. CONCLUSION The extraction rate of active material using optimized process is higher and suit for manufacturing.

Key concepts: Flos, Extraction (chemistry), Chromatography, Chemistry, Water extraction, Manufacturing process, High-performance liquid chromatography, Active ingredient

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