Determination of serum acute phase reaction protein in patients with pneumonia

【Objective】To study the diagnostic value of determinations of serum acute phase reactionprotein,such as complement 3(C3),complement 4(C4),prealbumin(PA) and C-reative protein(CRP),etc,in patients with pneumonia.【Methods】Serum levels of C3,C4,PA and CRP were determined by turbidimetry in 74 of other pneumonia and 30 normal persons.【Results】Serum concentrations of C3,C4,CRP and PA were(1.21 ± 0.51) g/L,(0.38 ± 0.26) g/L,(0.42 ± 0.26) mg/L and(376 ± 74.08) mg/L in noraml persons,respectively.Serum level of PA was significantly lower and levels of C4 and CRP significandy in patients with SARS higher than those in patients with other pneumonia and normal persons(P 0.01).There wasno significant difference in serum level of C3 between the three groups(P 0.05).【Conclusions】Determination of serum level of C4.CRP and PA in suspected patients is beneficial to early differentialdiagnosis for pneumonia.