Clinical distribution of bacteria and drug resistance in 2011 of Sichuan provincial people's hospital

To investigate the distribution and resistance to commonly used antibiotics of clinical isolates obtained from Sichuan Provincial People's Hospital. The bacteria strains isolated from clinics were collected.Identification and drug susceptibility test were performed by VITEK2-compact automatic analysis system and the results were analyzed according to CLSI 2011 by WHONET5.6 software. A total of 4461 bacterial isolates were obtained,which included 1741(39%)Gram-positive strains and 2720(61%)Gram-negative strains.The detection rates of Methicillin-resistant Staphylococcus aureus(MRSA)and coagulase-negative Staphylococcus(MRSCN)were 51.6% and 86.1% respectively.No vacomycin-resistant Staphylococcus strains were found.The resistance rates of Enterococcus faecium and Enterococcus faecalis to vancomycin were 4.3% and 1.8% respectively.No Linezolid-resistant Enterococcus were found;the resistance rates to Imipenem of E.coli and K.Pneumoniae isolates were 0.1% and 1.1% respectively;the resistance rate of Pseudomonas aeruginosa to carbapenems was around,while the drug resistance of A.baumannii was higher than that of P.aeruginosa. Drug resistance of bacterial isolated from our hospital is universal,areas,we should be rational use of drug monitoring data to provide a basis for clinical treatment.